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Title An acute exposure to glyphosate-based herbicide alters aromatase levels in testis and sperm nuclear quality
Author Estelle Cassault-Meyera, Steeve Gressa, Gilles-Éric Séralinia, Isabelle Galeraud-Denisa
Date 2014-07
Description We investigated the effects of a glyphosate-based herbicide after an 8-day exposure of adult rats. We have shown a significant and differential expression of aromatase in testis. We have observed a diminution of mRNA expression of nuclear markers in spermatozoa. These results suggest changes in androgen/estrogen balance and in sperm nuclear quality. The repetition of exposures of this herbicide could alter the mammalian reproduction.
Keywords Roundup; Glyphosate; Testis; Spermatozoa; Aromatase (P450 arom), Nuclear quality
URL http://www.sciencedirect.com/science/article/pii/S1382668914001227
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ID 7878