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Title Neuropathogenicity of non-viable Borrelia burgdorferi ex vivo
Author Geetha Parthasarathy Shiva Kumar Goud Gadila
Date 2022-01-13
Description Even after treatment, a proportion of Lyme disease patients suffer from symptoms collectively called Post-Treatment Lyme Disease Syndrome (PTLDS). A recent study demonstrated that non-viable remnants of Borrelia burgdorferi spirochetes are pathogenic to both CNS and PNS tissues, suggesting that for at least a subset of patients, B. burgdorferi fragments in the nervous system could be the cause of persistence of symptoms post-treatment, leading to long term health consequences.
Keywords tick, Lyme disease, Borrelia burgdorferi
URL https://www.nature.com/articles/s41598-021-03837-0
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